1 Hotels, the luxury lifestyle hotel brand inspired by nature, today announced the opening of 1 Hotel San Francisco, the mission-driven luxury hospitality brand's second California property and the City by the Bay's newest, most thoughtfully designed eco-friendly urban refuge. Integrating the best of sustainable design and architecture with extraordinary comfort and an unrivaled level of service, the property's 186 guest rooms and 14 suites capture panoramic views of the Bay Area's rolling hills, sweeping fog, inspiring architecture, and stunning natural beauty.